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Detroit vs Buffalo NFL Odds & Result – Sep 17, 2026

NFL game: Detroit at Buffalo on Thursday, September 17, 2026 at 8:15 PM ET (NFL Week 2). Rotation numbers 103 (Detroit) and 104 (Buffalo).

Final score

Line score
RotTeam12341H2HFinal
103Detroit010714102131
104Buffalo141377271441

Betting lines

Betting lines
MarketOpenCloseResult
SpreadBuffalo −3Buffalo −5.5Buffalo covered
Total52.554.5 (−115)▲ Over (72 pts)

The spread moved 2.5 points toward Buffalo, from Buffalo −3 to Buffalo −5.5; the total rose from 52.5 to 54.5. Buffalo won by 10 and covered the closing spread of −5.5, beating the number by 4.5 points. The teams combined for 72 points, going over the closing total of 54.5 by 17.5 points.

Half lines

First and second half lines
MarketOpenCloseResult
1st half spreadBuffalo −3.5 (+100)Buffalo −3.5 (−105)Buffalo covered
1st half total26.5 (−125)27 (−115)▲ Over
2nd half spreadBuffalo −2.5Detroit −0.5 (−120)Detroit covered
2nd half total26.527 (−120)▲ Over

More

"Close" is the last line before the game. Spreads read from the favorite's side. Information only.