College Football Results & Closing Lines – Thursday, October 22, 2026
3 NCAAF games on Thursday, October 22, 2026. Favorites 1–2 ATS · Overs 2–1.
Favorites ATS
1–2
against the closing spread
Over / under
2–1
overs – unders
Average total
60.0
closing total 54.2
Biggest cover
19
Liberty beat the line by 19
Biggest upset
+12.5
Appalachian St beat James Madison, a 12.5-point favorite
NCAAF games
| Rot | Team | Status | Score | By period | Spread | Total | Open | 1st half |
|---|---|---|---|---|---|---|---|---|
| 313 | James Madison | Final | 31 | 7 7 7 10 0 | −12.5 | o56.5▲ | −10 o/u 57.5 | 14 −7 |
| 314 | Appalachian St | 34 | 0 10 3 18 3 | +12.5✓ | u56.5 | +10 | 10 +7✓ | |
| 315 | East Carolina | Final | 34 | 10 6 8 10 0 | +10.5✓ | o55.5▲ | +9.5 o/u 53.5 | 16 +6.5✓ |
| 316 | Memphis | 41 | 0 3 17 14 7 | −10.5 | u55.5 | −9.5 | 3 −6.5 | |
| 415 | Liberty | Final | 34 | 14 0 10 10 | −9✓ | o50.5 | −10.5 o/u 49 | 14 −5.5✓ |
| 416 | Kennesaw St | 6 | 0 3 0 3 | +9 | u50.5▼ | +10.5 | 3 +5.5 |
ATS ✓ marks the side that covered the closing spread; ▲ over and ▼ under mark which side of the closing total hit; P is a push. Closing lines can differ a little from book to book.