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Louisville vs Mississippi NCAAF Odds & Result – Sep 6, 2026

College Football game: Louisville at Mississippi on Sunday, September 6, 2026 at 7:45 PM ET. Rotation numbers 229 (Louisville) and 230 (Mississippi).

Final score

Line score
RotTeam12341H2HFinal
229Louisville33181463238
230Mississippi0101417103141

Betting lines

Betting lines
MarketOpenCloseResult
SpreadMississippi −6.5Mississippi −6.5 (−115)Louisville covered
Total55.554.5▲ Over (79 pts)

The spread held at Mississippi −6.5 from open to close; the total dropped from 55.5 to 54.5. Louisville lost by 3 and covered the closing spread of +6.5, beating the number by 3.5 points. The teams combined for 79 points, going over the closing total of 54.5 by 24.5 points.

Half lines

First and second half lines
MarketOpenCloseResult
1st half spreadMississippi −4.5 (−105)Mississippi −3.5Mississippi covered
1st half total28.5 (−115)27.5▼ Under
2nd half spreadMississippi −3Mississippi −3Louisville covered
2nd half total24 (−115)24 (−120)▲ Over

More

"Close" is the last line before the game. Spreads read from the favorite's side. Information only.